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KCNN1

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

Synonymes:
KCa2.1, SK1, SKCA1, hSK1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3780) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
  • Mouse(84036) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • Rat(54261) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • domestic guinea pig(100715012) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • naked mole-rat(101717556) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • sheep(101112056) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • dog(484829) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • cow(408008) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
  • domestic cat(101085608) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Apamin, from bee venom, ≥95% (HPLC),
Espèce(s)
rat
Apamin, synthetic, ≥97% (HPLC),
Espèce(s)
rat

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-KCNN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-KCNN1 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human KCNN1,
Espèce(s)
human