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Merck

IL7R

interleukin 7 receptor

Synonymes:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
  • Mouse(16197) interleukin 7 receptor
  • Rat(294797) interleukin 7 receptor
  • sheep(101111126) interleukin 7 receptor
  • Domestic Rabbit(100343726) interleukin 7 receptor
  • domestic guinea pig(100714027) interleukin 7 receptor
  • naked mole-rat(101710077) interleukin 7 receptor
  • Zebrafish(100134973) interleukin 7 receptor
  • dog(612582) interleukin 7 receptor
  • domestic cat(101100697) interleukin 7 receptor
  • Horse(100034169) interleukin 7 receptor
  • cow(521554) interleukin 7 receptor
  • chicken(426054) interleukin 7 receptor

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ELISA

Référence du produit
Description
Espèce(s)
Mouse Il7r / Interleukin-7 Receptor Subunit Alpha ELISA Kit, ,
Espèce(s)
mouse
Human IL-7 R alpha ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CD127 (IL-7Ra) Antibody (mouse), FITC, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), PE-Cy7, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), Biotin, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), FITC, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human IL7R,
Espèce(s)
human