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Merck

IL7R

interleukin 7 receptor

Synonymes:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Espèce(s):
Human IL7R (3575), Mouse Il7r (16197), Rat Il7r (294797), sheep IL7R (101111126), Domestic Rabbit IL7R (100343726), domestic guinea pig Il7r (100714027), naked mole-rat Il7r (101710077), Zebrafish il7r (100134973), dog IL7R (612582), domestic cat IL7R (101100697) ...Plus
ID UniProtKB:
P16871, B2RCS6, B4DVT1, Q05CU8, Q6NSP4, Q6NWM0, Q6NWM1, Q6NWM2
ID du gène:
  • Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
  • Mouse(16197) interleukin 7 receptor
  • Rat(294797) interleukin 7 receptor
  • sheep(101111126) interleukin 7 receptor
  • Domestic Rabbit(100343726) interleukin 7 receptor
  • domestic guinea pig(100714027) interleukin 7 receptor
  • naked mole-rat(101710077) interleukin 7 receptor
  • Zebrafish(100134973) interleukin 7 receptor
  • dog(612582) interleukin 7 receptor
  • domestic cat(101100697) interleukin 7 receptor
  • Horse(100034169) interleukin 7 receptor
  • cow(521554) interleukin 7 receptor
  • chicken(426054) interleukin 7 receptor

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ELISA

Product Number
Description
Espèce(s)
RAB0816
Mouse Il7r / Interleukin-7 Receptor Subunit Alpha ELISA Kit, ,
Espèce(s)
mouse
RAB1530
Human IL-7 R alpha ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Product Number
Description
Espèces réactives
Application
MABF380
Anti-CD127 (IL-7Ra) Antibody (mouse), FITC, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
MABF540
Anti-CD127 (IL-7Ra) Antibody (mouse), PE-Cy7, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
MABF536
Anti-CD127 (IL-7Ra) Antibody (mouse), Biotin, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
MABF378
Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
MABF538
Anti-CD127 (IL-7Ra) Antibody (mouse), FITC, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Espèces réactives
mouse
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)

esiRNA

Product Number
Description
Espèce(s)
EHU066561
MISSION® esiRNA, targeting human IL7R,
Espèce(s)
human