GNRHR
gonadotropin-releasing hormone receptor
Synonymes:
GNRHR1, GRHR, HH7, LHRHR, LRHR
Espèce(s):
Human GNRHR (2798), Mouse Gnrhr (14715), Rat Gnrhr (81668), chicken GNRHR (427517), dog GNRHR (403718), cow GNRHR (281798), domestic cat GNRHR (101088838), Horse GNRHR (100033874), domestic guinea pig Gnrhr (100135532), naked mole-rat Gnrhr (101704341)
ID UniProtKB:
ID du gène:
- Human(2798) Summary: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14715) gonadotropin releasing hormone receptor
- Rat(81668) gonadotropin releasing hormone receptor
- chicken(427517) gonadotropin-releasing hormone receptor
- dog(403718) gonadotropin-releasing hormone receptor
- cow(281798) gonadotropin-releasing hormone receptor
- domestic cat(101088838) gonadotropin-releasing hormone receptor
- Horse(100033874) gonadotropin-releasing hormone receptor
- domestic guinea pig(100135532) gonadotropin releasing hormone receptor
- naked mole-rat(101704341) gonadotropin-releasing hormone receptor
- Domestic Rabbit(100009509) gonadotropin-releasing hormone receptor
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Goserelin for NMR identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Small Molecule - Antagonist
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-GRHR/LRHR antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human
Application
ELISA
western blot
western blot
Anti-GnRH-R Antibody, clone F1G4, clone FIG4, from mouse,
Espèces réactives
human
Application
ELISA
dot blot
flow cytometry
immunohistochemistry
western blot
dot blot
flow cytometry
immunohistochemistry
western blot
Anti-GNRHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-GNRHR antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
immunofluorescence
immunofluorescence
Proteins
Référence du produit
Description
Espèce(s)
[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, ≥97% (HPLC), powder,
Espèce(s)
mouse, human
esiRNA
Référence du produit
Description
Espèce(s)