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L4897

Sigma-Aldrich

Luteinizing hormone releasing hormone salmon

≥97% (HPLC)

Synonym(s):
GnRH, LH-RH, Gonadotropin releasing hormone, Gonadoliberin
Empirical Formula (Hill Notation):
C60H73N15O13
CAS Number:
Molecular Weight:
1212.31
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CO)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C(Cc6cnc[nH]6)NC(=O)C7CCC(=O)N7)C(=O)N8CCCC8C(=O)NCC(N)=O

InChI

1S/C60H73N15O13/c1-32(2)20-47(60(88)75-19-7-12-49(75)59(87)65-28-50(61)78)73-55(83)44(22-34-25-63-40-10-5-3-8-38(34)40)69-52(80)29-66-53(81)43(21-33-13-15-37(77)16-14-33)70-58(86)48(30-76)74-56(84)45(23-35-26-64-41-11-6-4-9-39(35)41)71-57(85)46(24-36-27-62-31-67-36)72-54(82)42-17-18-51(79)68-42/h3-6,8-11,13-16,25-27,31-32,42-49,63-64,76-77H,7,12,17-24,28-30H2,1-2H3,(H2,61,78)(H,62,67)(H,65,87)(H,66,81)(H,68,79)(H,69,80)(H,70,86)(H,71,85)(H,72,82)(H,73,83)(H,74,84)

InChI key

NMJREATYWWNIKX-UHFFFAOYSA-N

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2

Application

Luteinizing hormone releasing hormone (salmon) has been used to study the effect of LHRH (luteinizing hormone releasing hormone) in the brain of Podarcis sicula sicula (male) during reproduction. It has been used to study the hormonal regulation of PACAP (pituitary adenylate cyclase-activating polypeptide) and its receptor, PAC1 (adenylate cyclase activating polypeptide 1 (pituitary) receptor type I).

Packaging

1, 5 mg in glass bottle

Biochem/physiol Actions

Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.

Other Notes

Lyophilized from 0.5% acetic acid

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Repr. 1B

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

Weiming Zheng et al.
Reproductive sciences (Thousand Oaks, Calif.), 21(1), 41-51 (2013-05-22)
Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are expressed in the hypothalamus, the gonadotrope cells of the anterior pituitary gland, and the gonads, forming an autocrine-paracrine system in these tissues. Within the pituitary, PACAP functions either alone or synergistically
A Gobbetti et al.
Journal of reproduction and fertility, 101(3), 523-529 (1994-08-01)
The release of PGF2 alpha and PGE2, progesterone, androgens and oestradiol in vitro, and the aromatase activity in the brain of the male lizard Podarcis sicula sicula during three different phases of the reproductive period were evaluated. In addition, the
R S E Brown et al.
Journal of neuroendocrinology, 26(12), 898-908 (2014-09-11)
Hyperprolactinaemia is a major cause of infertility in both males and females, although the mechanism by which prolactin inhibits the reproductive axis is not clear. The aim of the present study was to test the hypothesis that elevated prolactin causes
R C Oliveira et al.
Journal of dairy science, 98(9), 6304-6314 (2015-07-21)
The prepartum supplementation of dairy cows with β-carotene was evaluated. Cows were blocked by parity and expected calving date and assigned to a treatment: β-carotene (1.2 g/cow per d) or control (no supplementation). The same total mixed ration batch was
N Basile et al.
Human reproduction (Oxford, England), 30(2), 276-283 (2014-12-21)
Can we use morphokinetic markers to select the embryos most likely to implant and are the results likely to be consistent across different clinics? Yes, morphokinetic markers can be used to select the embryos most likely to implant and the

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