CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
Synonymes:
LNCR2, NACHRA3, PAOD2
Espèce(s):
Human CHRNA3 (1136), Mouse Chrna3 (110834), Rat Chrna3 (25101), Zebrafish chrna3 (568467), dog CHRNA3 (482111), domestic cat CHRNA3 (100037403), cow CHRNA3 (282702), chicken CHRNA3 (386578), naked mole-rat Chrna3 (101701279), domestic guinea pig Chrna3 (100730977) ...Plus
ID UniProtKB:
ID du gène:
- Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
- Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
- Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
- dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- chicken(386578) cholinergic receptor, nicotinic, alpha 3
- naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
- Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
(−)-nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Espèce(s)
human, mouse, rat
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
dog, human, rabbit
Application
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
chicken, eel, human
Application
immunohistochemistry