Y0002401

Levocetirizine dihydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): (-)-Cetirizine dihydrochloride; 2-[2-[4-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride
• Empirical Formula (Hill Notation): C₂₁H₂₅ClN₂O₃·2HCl
• CAS Number: 130018-87-0
• Molecular Weight: 461.81
• MDL number: MFCD07366507

Properties

• grade: pharmaceutical primary standard
• manufacturer/tradename: EDQM
• application(s): pharmaceutical
• storage temp.: 2-8°C
• SMILES string: Cl.Cl.OC(=O)COCCN1CCN(CC1)[C@H](c2ccccc2)c3ccc(Cl)cc3
• InChI: 1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1
• InChI key: PGLIUCLTXOYQMV-GHVWMZMZSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. Compendial materials should be used for the purpose described in the appropriate monograph unless otherwise authorized by the National Competent Authority. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

e.g. pharmaceutical (small molecule)

Biochem/physiol Actions

Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.

Packaging

Unit quantity: 70mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.