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PHL89738

Naringenin

phyproof® Reference Substance

Synonym(s):

4′,5,7-Trihydroxyflavanone

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About This Item

Empirical Formula (Hill Notation):
C15H12O5
CAS Number:
67604-48-2
Molecular Weight:
272.25
MDL number:
MFCD00006844
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥95.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

InChI

1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

InChI key

FTVWIRXFELQLPI-UHFFFAOYSA-N

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application


  • Naringenin in metabolic syndrome studies: Research on the bioaccessibility and intestinal absorption of phenolic compounds, including naringenin, highlighted its potential in managing metabolic syndrome through simulated gastrointestinal digestion (Pais et al., 2024).

  • Antioxidant bioflavonoid research: Studies on naringenin have elucidated its antioxidant properties, offering insights into its protective effects against oxidative stress-related cellular damage (Wang et al., 2024).

  • Naringenin anti-inflammatory: A comprehensive review explored the inhibitory effects of naringenin on inflammatory pathways, particularly those triggered by SARS-CoV-2, showcasing its potential as an anti-inflammatory agent (Jantan et al., 2024).

  • Neurotransmitter metabolite research: Naringenin′s influence on cellular signaling pathways has been noted, with recent research indicating its role in the modulation of neurotransmitter activity and potential therapeutic applications in neurology and psychology (Pérez-Valero et al., 2024).

  • Naringenin pharmacological properties: Current reviews have focused on naringenin′s broad pharmacological applications, particularly in cancer therapy, highlighting its multifunctional capabilities as a natural flavonoid with potential therapeutic benefits (Wiciński et al., 2024).


Analysis Note

For this product we use the non-stereospecific CAS number. It is expected that the natural enantiomer is predominant, however the substance is prone to racemization in solution. The product is therefore not specified stereospecifically and is only recommended to be used for non-stereospecific analysis.

Other Notes

This compound is commonly found in plants of the genus: glycyrrhiza silybum thymus

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
136592955
117535258
112794123
77100709

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