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T8250

Sigma-Aldrich

D-Threonine

≥98% (TLC)

Synonym(s):

(2R,3S)-2-Amino-3-hydroxybutyric acid, D-α-Amino-β-hydroxybutyric acid

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About This Item

Empirical Formula (Hill Notation):
C4H9NO3
CAS Number:
Molecular Weight:
119.12
Beilstein:
1721643
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:

Quality Level

Assay

≥98% (TLC)

form

powder or crystals

technique(s)

UHPLC: suitable

color

white

mp

274 °C

solubility

H2O: soluble

SMILES string

C[C@H](O)[C@@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m0/s1

InChI key

AYFVYJQAPQTCCC-STHAYSLISA-N

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General description

D-Threonine is sweet and toxic in nature.It acts as an inhibitor of L-threonine dehydratase.

Application

D-Threonine has been used as a constituent of standard mix in Ultra-high performance liquid chromatography (UHPLC) system for quantification of amino acid racemization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kateryna Fesko et al.
Bioorganic & medicinal chemistry letters, 18(22), 5987-5990 (2008-09-02)
The Y265A mutant of alanine racemase (alrY265A) was evaluated as a catalyst for the synthesis of beta-hydroxy-alpha-amino acids. It promotes the PLP-dependent aldol condensation of glycine with a range of aromatic aldehydes. The desired products were obtained with complete stereocontrol
Alessandro Paiardini et al.
Biochimica et biophysica acta, 1647(1-2), 214-219 (2003-04-11)
Vitamin B(6)-dependent enzymes may be grouped into five evolutionarily unrelated families, each having a different fold. Within fold type I enzymes, L-threonine aldolase (L-TA) and fungal alanine racemase (AlaRac) belong to a subgroup of structurally and mechanistically closely related proteins
The Journal of Biological Chemistry, 244 (1969)
Fishmeal with different levels of biogenic amines in aquafeed: Comparison of feed protein quality, fish growth performance, and metabolism
Jasour M, et al.
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Test, 244 (1969)

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