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Key Documents

T3128

Sigma-Aldrich

Trizma® maleate

Synonym(s):

TRIS maleate salt, Tris(hydroxymethyl)aminomethane maleate salt, Tromethamine maleate salt

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About This Item

Linear Formula:
NH2C(CH2OH)3 · C4H4O4
CAS Number:
Molecular Weight:
237.21
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

Assay

≥99.5% NaOH basis (anhydrous, titration)

form

crystalline powder

solubility

water: 500 mg/mL, clear, colorless

SMILES string

NC(CO)(CO)CO.OC(=O)\C=C/C(O)=O

InChI

1S/C4H11NO3.C4H4O4/c5-4(1-6,2-7)3-8;5-3(6)1-2-4(7)8/h6-8H,1-3,5H2;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

HTMWOUBCEZXSHN-BTJKTKAUSA-N

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Application

Trizma® maleate has been used:
  • in the rehydration of sputum cytospin samples for immunocytochemical analysis
  • in the incubation of spinal cords sections prior to nucleoside diphosphatase assay
  • as a component of alkaline phosphate (AP) staining for embryonic stem cells

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model
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Journal of Neuroimmunology, 209(1-2), 65-80 (2009)
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