SRP0323
KDM4DL human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
Synonym(s):
KDM4D-like, KDM4DL, lysine (K)-specific demethylase 4E
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
Assay
≥70% (SDS-PAGE)
form
aqueous solution
mol wt
65 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KDM4E(390245)
General description
Human KDM4DL, also known as JMJDE (GenBank Accession No. NM_001161630), amino acids 2-337 with N-terminal GST-tag, MW=65 kDa, expressed in Sf9 cells using a Baculovirus expression system.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Barna D Fodor et al.
Genes & development, 20(12), 1557-1562 (2006-06-02)
Histone lysine trimethyl states represent some of the most robust epigenetic modifications in eukaryotic chromatin. Using a candidate approach, we identified the subgroup of murine Jmjd2 proteins to antagonize H3K9me3 at pericentric heterochromatin. H3K27me3 and H4K20me3 marks are not impaired
Sophie Beyer et al.
The Journal of biological chemistry, 283(52), 36542-36552 (2008-11-06)
Posttranslational histone modifications serve to store epigenetic information and control both nucleosome assembly and recruitment of non-histone proteins. Histone methylation occurs on arginine and lysine residues and is involved in the regulation of gene transcription. A dynamic control of these
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