SML0419

Ebselen Oxide

≥98% (HPLC)

• Synonym(s): 1-Oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one, Ebselen selenoxide, NSC 639772
• Empirical Formula (Hill Notation): C₁₃H₉NO₂Se
• CAS Number: 104473-83-8
• Molecular Weight: 290.18
• MDL number: MFCD18427988
• UNSPSC Code: 12352119
• PubChem Substance ID: 329825414
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 5 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: O=C1N(c2ccccc2)[Se](=O)c3ccccc13
• InChI: 1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
• InChI key: SBTLFLABILGUMK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Ebselen Oxide is an oxidative product of ebselen containing selenoxide group. Unlike ebselen, it lacks anti-oxidative property. Ebselen oxide may suppress human immunodeficiency virus-1 (HIV-1) replication by inhibiting HIV-1 capsid protein, similar to ebselen.

Ebselen oxide is a potent inhibitor of α-Methylacyl coenzyme A racemase (AMACR).

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301 + H331,H315,H335,H373,H410
• Precautionary Statements: P260 - P273 - P301 + P310 - P302 + P352 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable