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Key Documents

SAB5700484

Sigma-Aldrich

Anti-Phospho-EGFR-Y1086 antibody produced in rabbit

Synonym(s):

EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA

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About This Item

UNSPSC Code:
12352203

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

134
44
69
77

species reactivity

rat, human

concentration

0.72 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr1086)

Gene Information

human ... EGFR(1956)

General description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Immunogen

A phospho specific peptide corresponding to residues surrounding Y1086 of human EGFR

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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