SAB5600106

Anti-Phospho-AMPA Receptor antibody, GluR 1 subunit (Ser845), Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM296, purified immunoglobulin

• Synonym(s): Glutamate Receptor 1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• recombinant: expressed in HEK 293 cells
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: RM296, monoclonal; recombinant monoclonal
• form: buffered aqueous glycerol solution
• species reactivity: human
• technique(s): immunohistochemistry: 1:100-1:200; western blot: 1:100-1:200
• isotype: IgG
• NCBI accession no.: 2890
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer845)
• Gene Information: human ... GRIA1(2890)

Description

General description

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas.

Specificity

This antibody reacts to human Glutamate Receptor 1, AMPA Receptor (GluR1) only when phosphorylated at Ser845. There is no cross-reactivity to GluR1 that is not phosphorylated at Ser845. This antibody may also react to mouse or rat Phospho-AMPA Receptor (GluR1) (Ser845) as predicted by immunogen homology.

Immunogen

A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845).

Biochem/physiol Actions

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine.

Features and Benefits

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Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable