SAB4502609

Anti-NF-κB p65 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): NFKB3, RELA, TF65, nuclear factor NF-κ-B p65 subunit, p65
• MDL number: MFCD00802848
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 60 kDa
• species reactivity: human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI accession no.: Q04206
• UniProt accession no.: Q04206
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... RELA(5970)

Description

General description

Anti-NF-κB p65 antibody detects endogenous levels of total NF-κB p65 protein.

The NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) gene is mapped to human chromosome 11q13.1. It codes for a transcription factor, a subunit of NF-κB.

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.

Immunogen Range: 278-327

Application

Anti-NF-κB p65 antibody produced in rabbit has been used in western blot analysis.

Biochem/physiol Actions

NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) is associated with many fibrotic diseases such as liver fibrosis and cardiac fibrosis. Cell proliferation, inflammation, and apoptosis are some of the processes mediated by NF-κB p65. Dysregulation of the gene results in chronic inflammatory diseases, autoimmune disorders and cancer. NF-κB p65 plays an important role in NF-κB signaling.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable