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Key Documents

SAB4301117

Sigma-Aldrich

Anti-PIF1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

ATP-dependent DNA helicase PIF1, C15orf20, PIF

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

70 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:2000 (Cell Lysate)

isotype

IgG

accession no.

NP_001273425.1

UniProt accession no.

Q9H611

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PIF1(80119)

Specificity

The antibody detects endogenous level of total PIF1 protein.

Immunogen

Synthetic peptide corresponding to a region derived from 9-28 amino acids of Human ATP-dependent DNA helicase PIF1

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 1mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Eunae Park et al.
The Plant cell, 30(6), 1277-1292 (2018-05-17)
Phytochrome B (phyB) inhibits the function of phytochrome-interacting factors (PIFs) by inducing their degradation and sequestration, but the relative physiological importance of these two phyB activities is unclear. In an analysis of published Arabidopsis thaliana phyB mutations, we identified a
Woohyun Kim et al.
PLoS genetics, 15(7), e1008292-e1008292 (2019-07-25)
Red light promotes germination after activating phytochrome phyB, which destabilizes the germination repressor PIF1. Early upon seed imbibition, canopy light, unfavorable for photosynthesis, represses germination by stabilizing PIF1 after inactivating phyB. Paradoxically, later upon imbibition, canopy light stimulates germination after
Bo Chen et al.
Life sciences, 256, 117820-117820 (2020-06-09)
Neuroblastoma (NB) is one of the most common malignant tumors in children. Chemotherapy resistance is one of the significant challenges in the treatment of high-risk NB patients, and it is necessary to search for new valid targets for NB treatment.
Yongjian Qiu et al.
Nature communications, 8(1), 1905-1905 (2017-12-05)
Plant phytochromes are thought to transduce light signals by mediating the degradation of phytochrome-interacting transcription factors (PIFs) through the N-terminal photosensory module, while the C-terminal module, including a histidine kinase-related domain (HKRD), does not participate in signaling. Here we show
Jiancai Wang et al.
Cancer management and research, 12, 7827-7835 (2020-09-19)
Cervical cancer is a common malignancy in female and it is a serious disease threatening women's lives. We aimed to explore whether PIF1 helicase expression could affect cell proliferation and apoptosis, and whether its mechanisms were related to the expression
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