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Key Documents

SAB1402953

Monoclonal Anti-U2AF1 antibody produced in mouse

Name: Monoclonal Anti-U2AF1 antibody produced in mouse
Brand: SIGMA

clone 1C8, purified immunoglobulin, buffered aqueous solution

Synonym(s):

DKFZp313J1712, FP793, RN, RNU2AF1, U2AF35, U2AFBP

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1C8, monoclonal

form

buffered aqueous solution

mol wt

antigen ~37.11 kDa

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG1κ

NCBI accession no.

NM_006758

UniProt accession no.

Q01081

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... U2AF1(7307)

Immunogen

U2AF1 (NP_006749.1, 56 a.a. ~ 155 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACC

Physical form

Solution in phosphate buffered saline, pH 7.4

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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RECURRENT MUTATIONS IN THE U2AF1 SPLICING FACTOR IN MYELODYSPLASTIC SYNDROMES

Timothy A

Nature Genetics (2012)

U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.

Okeya-Owuor T

Leukemia (2015)

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.

Fei DL

PLoS Genetics (2016)

The L1TD1 Protein Interactome Reveals the Impor tance of
Post-transcriptional Regulation in Human Pluripotency

Maheswara Reddy Emani

Stem Cell Reports (2015)

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