RAB0748

Human TNNT1 / Troponin T, Slow Skeletal Muscle ELISA Kit

• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.35 ng/mL; standard curve range: 0.391-25 ng/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TNNT1(7138)

Description

General description

Troponin T1, slow skeletal type (TNNT1) is encoded by the gene mapped to human chromosome 19q13.4. The encoded protein is composed of 261 amino acids and is expressed specifically in slow skeletal muscle.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Troponin T plays a vital role in calcium regulation of striated muscle contraction and relaxation. The alternative splicing regulation of troponin T1, slow skeletal type (TNNT1) expression has been implicated in regulation of muscle contractility in physiological and pathophysiological adaptations. Mutation in the gene is associated with the development of Nemaline myopathy.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABWASH4 20X Wash Buffer (Item B)

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Statements: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable