Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

RAB0204

Sigma-Aldrich

Human GDF-15 / MIC-1  ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonym(s):

GDF-15, Growth/differentiation factor 15 , MIC-1, Macrophage inhibitory cytokine 1

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 1.1-800 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GDF15(9518)

General description

Human GDF-15 / MIC-1 ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine and/or cell and tissue lysates. Growth differentiation factor-15 (GDF-15) is a cytokine for stress-response. It elevates during an inflammatory response and tissue injury. GDF-15 is also associated with cardiometabolic risk. It is localized in the adipocytes, macrophages, cardiomyocytes and vascular smooth muscle cells.

Immunogen

Recombinant Human GDF15

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human GDF-15 / MIC-1ELISA (enzyme-linked immunosorbent assay) kit has been used in the quantification of circulating macrophage inhibitory cytokine-1 (MIC-1) in venous blood samples.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Increased expression of GDF-15 may mediate ICU-acquired weakness by down-regulating muscle microRNAs.
Bloch SA
Thorax, 70(3), 219-228 (2015)
Hilde Engerud et al.
PloS one, 14(1), e0210585-e0210585 (2019-01-16)
Better biomarkers are needed in order to identify patients with endometrial carcinoma at risk of recurrence and who may profit from a more aggressive treatment regimen. Our objective was to explore the applicability of plasma growth differentiation factor 15 (GDF-15)
Azza Abdel Gawad Tantawy et al.
Blood cells, molecules & diseases, 53(4), 189-193 (2014-07-30)
High expression of growth differentiation factor-15 (GDF-15) contributes to pathological iron overload in thalassemia. Sickle cell syndromes are characterized by increased levels of erythropoiesis, although the primary defect involves the destruction of mature erythrocytes. To determine serum GDF-15 in 35
Sébastien Jeay et al.
Cancer research, 78(21), 6257-6267 (2018-08-24)
Activation of p53 by inhibitors of the p53-MDM2 interaction is being pursued as a therapeutic strategy in p53 wild-type cancers. Here, we report distinct mechanisms by which the novel, potent, and selective inhibitor of the p53-MDM2 interaction HDM201 elicits therapeutic
Insulin resistance, type 1 and type 2 diabetes, and related complications 2015
Ndisang J F, et al.
Journal of Diabetes Research (2015)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service