R3380
Ribonucleoside vanadyl complexes
200 mM
Synonym(s):
vanadyl ribonucleoside complexes
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352200
NACRES:
NA.52
Related Categories
General description
Ribonucleoside vanadyl complexes are stable complexes formed between ribonucleotides. They are low molecular weight inhibitors of cellular ribonucleases (RNases) that are used for the isolation of RNA from cells.
Application
Ribonucleoside vanadyl complexes are used as ribonuclease inhibitors during cell lysis and mRNA purification, to protect mRNA during cDNA production, and to protect RNA during digestion of DNA by DNaseI.
Ribonucleoside vanadyl complexes has been used:
- as a component of lysis buffer for cell lines prior to Poly(U) pull down assay
- to inhibit nucleases prior to immunoprecipitation (IP) of m6A-containing RNA fragment
- as a component of hybridization buffer for human retinal slices
Biochem/physiol Actions
Ribonucleoside vanadyl complexes (RVC) elicits antimicrobial functionality by inhibiting ribosomal subunit formation and suppressing the growth of Staphylococcus aureus and Escherichia coli. It is also used as a preservative solution for tissues.
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Inhibition of intractable nucleases with ribonucleoside--vanadyl complexes: isolation of messenger ribonucleic acid from resting lymphocytes.
S L Berger et al.
Biochemistry, 18(23), 5143-5149 (1979-11-13)
Effect of ribonucleoside-vanadyl complexes on enzyme-catalyzed reactions central to recombinant deoxyribonucleic acid technology.
R S Puskas et al.
Biochemistry, 21(19), 4602-4608 (1982-09-14)
Hyone-Myong Eun
Enzymology Primer for Recombinant DNA Technology (1996)
DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells.
Fukuchi K
Biochimica et Biophysica Acta, 1404(3), 405-411 (1998)
SIRT1 functions as a negative regulator of eukaryotic poly (A) RNA transport
Shan P, et al.
Current Biology, 27(15), 2271-2284 (2017)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service