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Key Documents

PLA0116

Sigma-Aldrich

Rabbit anti-p400 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

CAG repeat protein 32, CAGH32, DKFZP434I225, KIAA1498, KIAA1818, P400, TNRC12, domino homolog, hDomino, p400 SWI2/SNF2-related protein, p400 kDa SWI2/SNF2-related protein, trinucleotide repeat containing 12, trinucleotide repeat-containing gene 12 protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human, mouse

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:5,000

accession no.

AAK97789.1

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... p400(57634)

Immunogen

The epitope recognized by PLA0116 maps to a region between residues 3075 and the C-terminus (residue 3124) of human E1A binding protein p400 using the numbering given in entry AAK97789.1 (GeneID 57634).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

p400 belongs to the SWI2/SNF2 family of chromatin remodeling proteins and is a component of the NuA4 histone acetyltransferase complex. In this complex p400 positively regulates transcription by modifying nucleosome structure. P400 has also been found to play a role in the p52-p21 pathway that regulates p21 transcription and senescence as well as the ARF-p53 pathway that couples cell proliferation to apoptosis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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