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Key Documents

P9372

Sigma-Aldrich

Anti-Potassium Channel KCa2.1 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-KCNN1, Anti-SK1, Anti-SKCa1

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41
clone:
polyclonal
application:
WB
species reactivity:
rat
technique(s):
western blot: 1:200 using rat brain cortex
citations:
2

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

western blot: 1:200 using rat brain cortex

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

Immunogen

synthetic peptide (C)DRPGSGKPP-TVSHRLGHRR corresponding to amino acid residues 75-93 of rat KCa2.1. The sequence homology with mouse is 17/19 residues identical. Human is 12/19 residues identical.

Physical form

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.025% sodium azide.

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Storage Class Code

10 - Combustible liquids


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Amalia M Dolga et al.
The Journal of biological chemistry, 288(15), 10792-10804 (2013-02-23)
Small conductance calcium-activated potassium (SK2/K(Ca)2.2) channels are known to be located in the neuronal plasma membrane where they provide feedback control of NMDA receptor activity. Here, we provide evidence that SK2 channels are also located in the inner mitochondrial membrane
R Khanna et al.
The Journal of biological chemistry, 274(21), 14838-14849 (1999-05-18)
Human T lymphocytes express a Ca2+-activated K+ current (IK), whose roles and regulation are poorly understood. We amplified hSK4 cDNA from human T lymphoblasts, and we showed that its biophysical and pharmacological properties when stably expressed in Chinese hamster ovary

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