Skip to Content
MilliporeSigma
All Photos(4)

Key Documents

N3002

Sigma-Aldrich

Bis(p-nitrophenyl) phosphate sodium salt

chromogenic, ≥99% (TLC), powder

Synonym(s):

BNPP sodium salt, Sodium bis(4-nitrophenyl) phosphate

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
C12H8O8N2PNa
CAS Number:
Molecular Weight:
362.16
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

Bis(p-nitrophenyl) phosphate sodium salt, ≥99% (TLC)

Quality Level

Assay

≥99% (TLC)

form

powder

impurities

≤0.05% free p-nitrophenol

solubility

water: 20 mg/mL, clear to very slightly hazy

storage temp.

−20°C

SMILES string

[Na].OP(=O)(Oc1ccc(cc1)N(=O)=O)Oc2ccc(cc2)N(=O)=O

InChI

1S/C12H9N2O8P.Na.H/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18;;/h1-8H,(H,19,20);;

InChI key

NXXNKMXTNUUECE-UHFFFAOYSA-N

Related Categories

Application

Bis(p-nitrophenyl) phosphate sodium salt has been used as a substrate for the estimation of phosphodiesterase (PDE) activity. It has also been used as a substrate in PDE inhibition assay.

Substrates

Phosphodiesterase substrate

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Nucleotidase and DNase activities in Brazilian snake venoms
Sales PB, et al.
Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP, 147(1), 85-95 (2008)
Elution of tightly bound solutes from concanavalin A Sepharose: Factors affecting the desorption of cottonmouth venom glycoproteins
Soper AS and Aird SD
Journal of Chromatography A, 1154(1-2), 308-318 (2007)
6-Nitrobenzimidazole derivatives: Potential phosphodiesterase inhibitors: Synthesis and structure-activity relationship
Khan KM, et al.
Bioorganic & Medicinal Chemistry, 20(4), 1521-1526 (2012)
Michael Subat et al.
Inorganic chemistry, 47(11), 4661-4668 (2008-05-09)
Previously reported mono- and dinuclear Zn(II), Cu(II), and Ni(II) complexes of 1,4,7,10-tetrazacyclododecane ([12]aneN4 or cyclen) with different heterocyclic spacers (triazine, pyridine) of various lengths (bi- and tripyridine) or an azacrown-pendant have been tested for the hydrolysis of bis(4-nitrophenyl)phosphate (BNPP) under
Kayoko Ohura et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(2), 323-331 (2009-11-20)
Both mRNA and protein levels of the carboxylesterase (CES) isozymes, hCE1 and hCE2, in Caco-2 cells increase in a time-dependent manner, but hCE1 levels are always higher than those of hCE2. In human small intestine, however, the picture is reversed

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service