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MSQC1

Sigma-Aldrich

MS Qual/Quant QC Mix

Proteomics MRM LC-MS Calibration Standard

Synonym(s):

QC Mix

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.24

form

solid

Quality Level

200

quality

Proteomics MRM LC-MS Calibration Standard

storage temp.

−20°C

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Application

This product is optimized to assess platform characteristics, including:
  • Repeatability/Reproducibility between runs
  • System stability (drift, chromatography, signal intensity, sensitivity, etc.)
  • Inter- and intra- platform and lab comparisons
To view a poster by Tobias Kockmann and colleagues at ETH Zurich on the use of MSQC1 in multiple LC-MS platforms, please visit this poster link.

Features and Benefits

General

Complexity
  • Defined mixture gives confidence in your instruments analysis

Qualitative

Mixture of 6 tryptically digested human proteins (FASTA file)
  • Low complexity, defined mixture
  • 25 fold concentration range
  • C18 purified

14 SIL peptides
  • SIL peptides span a concentration range greater than three orders of magnitude (Table 1)
  • 2 - 3 peptides per protein

Quantitative

  • MRM settings provided (xls)
  • MRM transitions provided (file above)
  • Light : Heavy ratios from 50:1 to 1:5

Components

Each vial contains 6 pre-digested (trypsin) human proteins plus 14 corresponding stable isotope labeled (SIL) peptides (7-8 μg total dried in a 0.5 mL vial).

Quality

Up to 100 uses based upon the recommended reconstitution method

Legal Information

This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.

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Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tobias Kockmann et al.
Proteomics, 16(15-16), 2183-2192 (2016-05-01)
Quantitative mass spectrometry is a rapidly evolving methodology applied in a large number of omics-type research projects. During the past years, new designs of mass spectrometers have been developed and launched as commercial systems while in parallel new data acquisition

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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