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Key Documents

H4542

Sigma-Aldrich

Cytochrome P450 2C9*3 (I359L), human

recombinant, expressed in E. coli

Synonym(s):

Cytochrome P450, purified, soluble, CYP2C9 I359L, CYP2C9 Il359Leu

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About This Item

CAS Number:
9035-51-2
UNSPSC Code:
12352204
NACRES:
NA.54

biological source

human

Quality Level

200

recombinant

expressed in E. coli

description

purified, soluble

form

liquid

specific activity

3-56 units/mg protein

mol wt

54423.1 g/mol

concentration

3.5-25 mg protein/mL (protein)
50-150 nmol/mL
6-14 nmol/mg protein (specific content)

NCBI accession no.

NP_000762.2

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... CYP2C9(1559)

General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Unit Definition

One unit will convert 1.0 nanomole of diclofenac (2-(2,6-dichloranilino) phenylacetic acid) 4`-hydroxylated product per minute at pH 7.4 at 37 °C.

Other Notes

Visit our drug metabolism resources: www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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