G8377

Guanosine 5′-monophosphate disodium salt hydrate

from yeast, ≥99%

• Synonym(s): 5′-GMP-Na₂, 5′-Guanylic acid disodium salt hydrate
• Empirical Formula (Hill Notation): C₁₀H₁₂N₅Na₂O₈P · xH₂O
• CAS Number: 5550-12-9
• Molecular Weight: 407.18 (anhydrous basis)
• Beilstein: 3586801
• EC Number: 226-914-1
• MDL number: MFCD00151238
• UNSPSC Code: 41106305
• PubChem Substance ID: 24895338
• NACRES: NA.51

Properties

• biological source: yeast
• Assay: ≥99%
• form: powder
• solubility: H₂O: soluble 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: room temp
• SMILES string: O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1
• InChI: 1S/C10H14N5O8P.2Na.H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);;;1H2/q;2*+1;/p-2/t3-,5-,6-,9-;;;/m1.../s1
• InChI key: MEKWJTZTMVQYSU-CYCLDIHTSA-L

Description

Application

Guanosine 5′-monophosphate is suitable for use in:

• the measurement of density and viscosity of nucleotide and along with the furanose sugar from 0.0004 to 0.0014mol/kg solution at 288.15, 293.15 and 298.15K at atmospheric pressure
• the detection and validation of a transcreener assay for detection of AMP- and GMP-producing enzymes
• the preparation of nucleotide standard during the quantitative profiling of nucleotides using capillary IC-MS/MS

Biochem/physiol Actions

Guanosine 5′-monophosphate (GMP) is a ribonucleoside monophospate which upon phosphorylation to GTP becomes incorporated into ribonucleic acids (RNAs) by various RNA polymerase(s). Guanosine-5′-monophosphate (GMP) can be used to study modulation of glutamatergic neurotransmission.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves