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E2888

Sigma-Aldrich

Earle′s Balanced Salts

With sodium bicarbonate, liquid, sterile-filtered, suitable for cell culture

Synonym(s):

EBSS

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About This Item

MDL number:
UNSPSC Code:
12352207
NACRES:
NA.75

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

components

phenol red: 0.011 g/L
glucose: 1.0 g/L (Dextro)
NaHCO3: 2.2 g/L

shipped in

ambient

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General description

Balanced Salt solution participates in providing a buffer system to maintain the medium in optimum pH range (7.2-7.6), irrigating and diluting while maintaining the intra- and extracellular osmotic balance. It helps to maintain the normal cell metabolism by giving water and bulk inorganic ions. Balanced Salt solution provides the energy source for cell metabolism by supplying carbohydrates such as glucose.

Application

Earle′s Balanced Salts has been used:
  • to incubate hepatocellular carcinoma cell line
  • as a component of embryo culture medium for washing rabbit embryos
  • to culture mouse embryonic neuroretina

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yunchen Le et al.
Cell death & disease, 9(6), 666-666 (2018-06-06)
Amino-acid metabolism plays a vital role in mammalian target of rapamycin (mTOR) signaling, which is the pivot in colorectal cancer (CRC). Upregulated chaperone-mediated autophagy (CMA) activity contributes to the regulation of metabolism in cancer cells. Previously, we found that sorting
Ann V Isaac et al.
Biochemical and biophysical research communications, 494(3-4), 656-662 (2017-10-28)
The sperm DNA integrity post cryopreservation of human semen samples is one of the serious concerns in human infertility treatment. In the present study, the beneficial effects of zinc oxide nanoparticles in preserving the functional ability of spermatozoa was explored.
Ling Li et al.
The Journal of biological chemistry, 292(33), 13774-13783 (2017-07-15)
Autophagy has been shown to be important for normal homeostasis and adaptation to stress in the kidney. Yet, the molecular mechanisms regulating renal epithelial autophagy are not fully understood. Here, we explored the role of the stress-responsive transcription factor forkhead
Jun Song et al.
Scientific reports, 7(1), 12202-12202 (2017-09-25)
Immunodeficient mice have been used predominantly in biomedical research. Realizing that large animal species may have an enhanced ability to predict clinical outcome relative to mice, we worked to develop immunodeficient rabbits by CRISPR/Cas9. We first demonstrated that multiplex embryo
Chinwendu Nwadike et al.
Molecular and cellular biology, 38(10) (2018-03-07)
Autophagy maintains metabolism in response to starvation, but each nutrient is sensed distinctly. Amino acid deficiency suppresses mechanistic target of rapamycin complex 1 (MTORC1), while glucose deficiency promotes AMP-activated protein kinase (AMPK). The MTORC1 and AMPK signaling pathways converge onto

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