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Key Documents

AV35790

Sigma-Aldrich

Anti-POLR2I (AB1) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Polymerase (RNA) II (DNA directed) Polypeptide I, 14.5 kDa, Anti-RPB9, Anti-hRPB14.5

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

14 kDa

species reactivity

dog, horse, rat, rabbit, mouse, guinea pig, human, bovine

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_006224

UniProt accession no.

P36954

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... POLR2I(5438)

Immunogen

Synthetic peptide directed towards the N terminal region of human POLR2I

Biochem/physiol Actions

POLR2I is a subunit of RNA polymerase II and mediates the formation of DNA binding domain of the enzyme. It regulates the mRNA synthesis in the eukaryotes.

Sequence

Synthetic peptide located within the following region: ACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQ

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J Acker et al.
Nucleic acids research, 21(23), 5345-5350 (1993-11-25)
The structure of the gene encoding the 14.5 kDa subunit of the human RNA polymerase II (or B) has been elucidated. The gene consists of six exons, ranging from 52 to over 101 bp, interspaced with five introns ranging from

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