AV34717
Anti-TRIM31 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Trim31 Antibody, Trim31 Antibody - Anti-TRIM31 antibody produced in rabbit, Anti-Tripartite motif-containing 31
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All Photos(3)
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
48 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TRIM31(11074)
General description
TRIM31 is a protein containing zinc-binding, B-box type, RING, and coiled-coil domains. Alterations in TRIM31 gene have been implicated in attention deficit/hyperactivity disorder (ADHD), whereas the changes in protein levels have been linked to gastric and non-small cell lung cancers.
Rabbit Anti-TRIM31 antibody recognizes human, bovine, and mouse TRIM31.
Rabbit Anti-TRIM31 antibody recognizes human, bovine, and mouse TRIM31.
Immunogen
Synthetic peptide directed towards the N terminal region of human TRIM31
Application
Rabbit Anti-TRIM31 antibody is suitable for western blot (0.5 μg/ml) and IHC (4-8 μg/ml) assays.
Biochem/physiol Actions
TRIM31 encodes for a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus.
Sequence
Synthetic peptide located within the following region: CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHR
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Hui Li et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(6), 5747-5752 (2014-02-26)
The present study aims to investigate expression pattern and biological roles of TRIM31 in human non-small cell lung cancer (NSCLC). We examined TRIM31 expression in 116 NSCLC tissues and 20 corresponding normal lung tissues by immumohistochemistry. We found TRIM31 downregulation
Thais S Rizzi et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 156(2), 145-157 (2011-02-09)
Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible
Shenglan Zeng et al.
Redox biology, 45, 102058-102058 (2021-07-05)
Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological conditions. However, whether TRIM31 plays a role in ischemic stroke progression is not clarified. Here we demonstrated that TRIM31 was significantly downregulated in the ischemic brain and the
Takeyuki Sugiura
Cell biology international, 35(7), 657-661 (2011-01-15)
TRIM (tripartite motif) family proteins, comprising RING finger, B-box and coiled-coil domains, are involved in various cellular processes including tumour development and antiviral response. One of the family proteins, TRIM31, was originally identified as a gene induced by growth-suppressive retinoid.
Shigao Yang et al.
Science advances, 5(5), eaav7999-eaav7999 (2019-06-01)
The mitochondrial antiviral signaling protein (MAVS) orchestrates host antiviral innate immune response to RNA virus infection. However, how MAVS signaling is controlled to eradicate virus while preventing self-destructive inflammation remains obscure. Here, we show that protein geranylgeranylation, a posttranslational lipid
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