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A5575

Sigma-Aldrich

Methyl δ-aminolevulinate hydrochloride

≥98% (TLC)

Synonym(s):

5-Amino-4-oxopentanoic acid methyl ester, 5-Aminolevulinic acid methyl ester

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About This Item

Empirical Formula (Hill Notation):
C6H11NO3 · HCl
CAS Number:
79416-27-6
Molecular Weight:
181.62
EC Number:
279-151-1
MDL number:
MFCD00012868
UNSPSC Code:
12352209
PubChem Substance ID:
24890995
NACRES:
NA.26

product name

Methyl δ-aminolevulinate hydrochloride, ≥98% (TLC)

Quality Level

200

Assay

≥98% (TLC)

form

powder

color

white

storage temp.

2-8°C

SMILES string

Cl.COC(=O)CCC(=O)CN

InChI

1S/C6H11NO3.ClH/c1-10-6(9)3-2-5(8)4-7;/h2-4,7H2,1H3;1H

InChI key

UJYSYPVQHFNBML-UHFFFAOYSA-N

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Related Categories

Biochem/physiol Actions

Methyl δ-aminolevulinate (methyl-ALA, MAL) and 5-Aminolevulinic acid (5-ALA) are commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yoojin Lee et al.
Seminars in cutaneous medicine and surgery, 30(4), 199-209 (2011-11-30)
Photodynamic therapy (PDT) involves the activation of a photosensitizing drug, which preferentially localizes to diseased skin, by irradiation with light to cause selective cytotoxic damage. Since its discovery in the early 20th century and the development of topical photosensitizers 2
Nicola Bruscino et al.
Photodermatology, photoimmunology & photomedicine, 27(6), 334-335 (2011-11-19)
The case we report is about a female patient, 69 years old, who had a hypertrophic scarring on the right cheek because of a bite by her dog. She had attempted many types of topical and intralesional treatments but without
Hui-Lin Ding et al.
Photodiagnosis and photodynamic therapy, 8(4), 343-346 (2011-11-30)
Acne vulgaris is a common dermatological disorder. Topical photodynamic therapy (PDT)-mediated with aminolevulinic acid (ALA) or methyl aminolevulinic acid (MAL) has been successfully used in the treatment of moderate to severe acne. The purpose of this case report is to
Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice: part I. Acne vulgaris: when and why consider photodynamic therapy?
Sakamoto FH, Lopes JD, Anderson RR.
Journal of the American Academy of Dermatology, 63, 193-194 (2010)
Romualdas Rudys et al.
Journal of biomedical optics, 20(5), 051035-051035 (2015-02-13)
This study combines several fluorescence detection methods to distinguish structural features of the synovium and cartilage tissues and to visualize the localization of endogenous porphyrins in the sensitized tissues. Specimens of synovium and cartilage tissues obtained from rabbits with antigen-induced

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