Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

A4929

Supelco

N,N′-Bis(acryloyl)cystamine

BioReagent, suitable for electrophoresis

Synonym(s):

2,2′-(Bisacrylamino)diethyl disulfide, BAC, Bis(2-acrylamidoethyl) disulfide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H16N2O2S2
CAS Number:
60984-57-8
Molecular Weight:
260.38
EC Number:
262-546-8
MDL number:
MFCD00036225
UNSPSC Code:
12352116
PubChem Substance ID:
24890926
NACRES:
NA.25

product line

BioReagent

Quality Level

200

form

powder

suitability

suitable for electrophoresis

storage temp.

−20°C

SMILES string

C=CC(=O)NCCSSCCNC(=O)C=C

InChI

1S/C10H16N2O2S2/c1-3-9(13)11-5-7-15-16-8-6-12-10(14)4-2/h3-4H,1-2,5-8H2,(H,11,13)(H,12,14)

InChI key

DJVKJGIZQFBFGS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

BAC is used as a reversible cross-linker for polyacrylamide gels, to simplify isolation of macromolecules separated on the gels. The disulfide linkage can be broken with a suitable reducing agent. A 1-g slice of a 4% (12:1) gel will dissolve in 5 mL of 100 mM DTT in TBE (pH 8.3) in less than 30 min.
BAC is used as a reversible cross-linker for polyacrylamide gels. The disulfide linkage can be broken with a suitable reducing agent. A 12:1 ratio of acrylamide:BAC is recommended for DNA purification. A one gram slice of a 4% gel will dissolve in 5 mL of 100 mM DTT, TBE solution (pH 8.3) in less than 30 min. The pH of 8.3 is optimum for rapid dissolution of the gel.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sebastian Ribi et al.
Oncotarget, 6(10), 7727-7740 (2015-03-13)
Somatic mutations of TP53 are among the most common in cancer and germline mutations of TP53 (usually missense) can cause Li-Fraumeni syndrome (LFS). Recently, recurrent genomic rearrangements in intron 1 of TP53 have been described in osteosarcoma (OS), a highly
Jinhong Li et al.
The New phytologist, 208(1), 137-148 (2015-04-14)
Heteromorphic flower development in Primula is controlled by the S locus. The S locus genes, which control anther position, pistil length and pollen size in pin and thrum flowers, have not yet been characterized. We have integrated S-linked genes, marker
David W Cescon et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(11), 2499-2505 (2015-03-06)
Genomic profiling of lung squamous cell carcinomas (SCC) has identified NRF2 pathway alterations, which activate oxidative response pathways, in one third of tumors. Preclinical data suggest these tumors may be resistant to platinum-based chemotherapy. We evaluated the clinical relevance of
Wesley C Warren et al.
Genome research, 25(12), 1921-1933 (2015-09-18)
We describe a genome reference of the African green monkey or vervet (Chlorocebus aethiops). This member of the Old World monkey (OWM) superfamily is uniquely valuable for genetic investigations of simian immunodeficiency virus (SIV), for which it is the most
Nick Orr et al.
Human molecular genetics, 24(10), 2966-2984 (2015-02-06)
We recently identified a novel susceptibility variant, rs865686, for estrogen-receptor positive breast cancer at 9q31.2. Here, we report a fine-mapping analysis of the 9q31.2 susceptibility locus using 43 160 cases and 42 600 controls of European ancestry ascertained from 52
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service