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Key Documents

A214680

Sigma-Aldrich

DMT-2′O-TC-rA(ib) Phosphoramidite

configured for PerkinElmer

Synonym(s):

DMT-2′O-TC-rA(ib) Amidite

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About This Item

Empirical Formula (Hill Notation):
C49H61N8O10PS2
CAS Number:
Molecular Weight:
1017.16
UNSPSC Code:
41116105

Assay

≥98% (31P-NMR)
≥98.0% (reversed phase HPLC)

Quality Level

technique(s)

oligo synthesis: suitable

impurities

≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR)
≤-0.5% Impurity 3′-TC Isomer (reversed phase HPLC)

compatibility

configured for PerkinElmer

nucleoside profile

base: adenosine
base protecting group: isobutyryl
2' protecting group: TC
5' protecting group: DMT

storage temp.

-10 to -25°C

SMILES string

S=C(N1CCS(CC1)(=O)=O)O[C@@H]2[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](O[C@H]2N3C4=C(N=C3)C(NC(C(C)C)=O)=NC=N4)COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7

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