Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

96286

Sigma-Aldrich

Z-Gly-Pro-4-nitroanilide

≥99.0% (TLC), powder or crystals

Synonym(s):

Z-glycyl-L-proline-4-nitroanilide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C21H22N4O6
CAS Number:
Molecular Weight:
426.42
Beilstein:
4606381
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

Z-Gly-Pro-4-nitroanilide, ≥99.0% (TLC)

Quality Level

Assay

≥99.0% (TLC)

form

powder or crystals

storage temp.

−20°C

SMILES string

[O-][N+](=O)c1ccc(NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)OCc3ccccc3)cc1

InChI

1S/C21H22N4O6/c26-19(13-22-21(28)31-14-15-5-2-1-3-6-15)24-12-4-7-18(24)20(27)23-16-8-10-17(11-9-16)25(29)30/h1-3,5-6,8-11,18H,4,7,12-14H2,(H,22,28)(H,23,27)/t18-/m0/s1

InChI key

UTXSFKPOIVELPQ-SFHVURJKSA-N

Application

Z-Gly-Pro-4-nitroanilide has been used as a supplement in hydrolysate solution for determining the prolyl endopeptidase inhibitory activity assay.

Biochem/physiol Actions

Z-Gly-Pro-4-nitroanilide is a substrate for prolyl endopeptidase (PEP).

Other Notes

Substrate for prolyl endopeptidase

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Duleepa Pathiraja et al.
Journal of biotechnology, 308, 124-129 (2019-12-15)
Amatoxins are ribosomally synthesized and post-translationally modified peptides (RiPPs) found in poisonous mushrooms. These cyclic peptides are potent inhibitors of RNA polymerase II transcriptional activity. Though the macrocyclization of amatoxin is extensively studied, little is known about its subsequent post-translational
K. Hauzer et al.
Collection of Czechoslovak Chemical Communications, 47, 1139-1139 (1982)
Isolation of prolyl endopeptidase inhibitory peptides from a sodium caseinate hydrolysate
Hsieh CH, et al.
Food & Function, 7(1), 565-573 (2016)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service