71790

Sodium nucleinate

• Synonym(s): Ribonucleic acid sodium salt
• MDL number: MFCD00148224
• UNSPSC Code: 12352106
• NACRES: NA.25

Properties

• form: powder
• Quality Level: 100
• loss: ~5% loss on drying, 20 °C (HV)
• solubility: H₂O: 0.1 g/mL, clear to turbid, brown-yellow (hot)
• storage temp.: 2-8°C

Description

General description

Sodium nucleinate is a derivative of tetrahydrophthalazine.

Application

<ul>
<li><strong>Tetrahydrophthalazine derivative &quot;sodium nucleinate&quot; exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (Jukic et al., 2012).</li>
<li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (Jukic et al., 2011).</li>
</ul>

Biochem/physiol Actions

Sodium nucleinate (SN) serves as an immunomodulatory substance, that possess anti-inflammatory effects.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves