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57857

Sigma-Aldrich

Lithium iodoacetate

≥97.0% (NT)

Synonym(s):

Iodoacetic acid lithium salt

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About This Item

Linear Formula:
ICH2COOLi
CAS Number:
65749-30-6
Molecular Weight:
191.88
Beilstein:
4208524
EC Number:
265-905-7
MDL number:
MFCD00037273
UNSPSC Code:
12352103
PubChem Substance ID:
57651632
NACRES:
NA.25

Quality Level

200

Assay

≥97.0% (NT)

impurities

≤3% water

mp

239 °C (dec.) (lit.)
~245 °C (dec.)

SMILES string

[Li+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Li/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

RZCFQIDTJPHHFJ-UHFFFAOYSA-M

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Application

Lithium iodoacetate, a halogenacetate, is a lithium salt of iodoacetate that may be used in the study of cysteine peptidases.

Caution

May discolor to yellow on storage

Other Notes

Sales restrictions may apply

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ehrenberg et al.
Acta crystallographica. Section B, Structural science, 55(Pt 4), 517-524 (2000-08-06)
Most halogenoacetates of alkali salts readily undergo a thermally induced polymerization reaction to poly-(hydroxyacetic acid) in the solid state. The lithium salts represent a remarkable exception. The crystal structures of lithium chloroacetate, lithium bromoacetate and lithium iodoacetate were determined ab
Yun Ju Woo et al.
Experimental & molecular medicine, 43(10), 561-570 (2011-07-29)
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Sébastien Goutal et al.
Drug delivery and translational research, 8(3), 536-542 (2018-01-03)
Elacridar (GF120918) is a highly potent inhibitor of both P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2), the main efflux transporters expressed at the blood-brain barrier (BBB). Elacridar shows very low aqueous solubility, which complicates its formulation for i.v. administration.
Sébastien Goutal et al.
Journal of pharmaceutical and biomedical analysis, 123, 173-178 (2016-02-26)
In clinical practice, rifampicin exposure is estimated from its concentration in venous blood samples. In this study, we hypothesized that differences in rifampicin concentration may exist between arterial and venous plasma. An HPLC-UV method for determining rifampicin concentration in plasma
Runqiang Yang et al.
Journal of the science of food and agriculture, 91(13), 2437-2442 (2011-06-28)
Proteases have become an essential part of the modern food and feed industry, being incorporated in a large and diversified range of products for human and animal consumption. The objective of this study was to purify and characterise a protease

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