443R-1

Nanog (EP225) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP225, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (443R-14); vial of 0.1 mL concentrate Research Use Only (443R-14-RUO); vial of 0.5 mL concentrate (443R-15); vial of 1.0 mL concentrate (443R-16); vial of 1.0 mL concentrate Research Use Only (443R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (443R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (443R-17); vial of 7.0 mL pre-dilute ready-to-use (443R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (443R-18-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)
• isotype: IgG
• control: seminoma
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: human ... NANOG(79923)

Description

General description

Nanog is a transcription factor homeoprotein that is involved in maintaining embryonic stem cell pluripotency and self-renewal. Embryonic stem cells with a deleted Nanog gene lose pluripotency. Conversely, embryonic stem cells that are forced to differentiate will downregulate Nanog expression. Nanog expression has been shown to be absent in normal adult organ tissues, but positive expression in undifferentiated germ cell tumors such as seminoma, dysgerminoma and embryonal carcinoma has been noted. Therefore, Nanog may be used as an aid in the determination of undifferentiated tumors of germ cell origin from non-germ cell tumors.

Quality

IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable