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385M-1

Sigma-Aldrich

SALL4 (6E3) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

6E3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (385M-14)
vial of 0.5 mL concentrate (385M-15)
bottle of 1.0 mL predilute (385M-17)
vial of 1.0 mL concentrate (385M-16)
bottle of 7.0 mL predilute (385M-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1

control

dysgerminoma, seminoma

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... SALL4(57167)

Related Categories

General description

Sal-like protein 4 (SALL4) is a zinc-finger transcription factor that serves as a master regulator of embryonic pluripotency and is involved in processes associated with stem cell activities. SALL4 expression in germ cells makes it a useful marker for germ cell tumors such as seminoma, embryonal carcinoma, yolk sac tumors, and teratomas. SALL4 expression is also seen in the spermatogonia of the normal testis.

Quality


IVD
IVD
IVD
RUO

Linkage

SALL4 Positive Control Slides, Product No. 385S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

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Wei Cui et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(12), 1585-1592 (2006-09-26)
SALL4, a newly identified zinc-finger transcriptional factor important for embryonic development, is mapped to chromosome 20q13. Previously, we reported that SALL4 was constitutively expressed in acute myeloid leukemia and SALL4 transgenic mice developed acute myeloid leukemia. In this study, we
Dengfeng Cao et al.
The American journal of surgical pathology, 33(6), 894-904 (2009-03-20)
Ovarian primitive germ cell tumors (GCTs) are uncommon tumors and sometimes pose diagnostic challenges. Among them, yolk sac tumor (YST) poses the greatest diagnostic difficulty and can be mistaken for clear cell carcinoma (CCC). Current immunohistochemical markers such as alpha-fetoprotein
Dengfeng Cao et al.
The American journal of surgical pathology, 33(7), 1065-1077 (2009-04-25)
The diagnosis of testicular germ cell tumors (GCTs) sometimes can be challenging without ancillary markers. Here we performed an immunohistochemical study of a novel stem cell marker SALL4 in a large series of 110 primary testicular GCTs (65 pure and

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