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317616

Sigma-Aldrich

D.P.X.

Neutral mounting medium

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About This Item

EC Number:
215-535-7
MDL number:
MFCD00135554
UNSPSC Code:
12171500
NACRES:
NA.47

biological source

synthetic

Quality Level

100

form

viscous liquid

color

yellow

refractive index

n20/D 1.521 (lit.)

density

0.904 g/mL at 25 °C (lit.)

application(s)

hematology
histology

storage temp.

room temp

General description

D.P.X is a mixture of distyrene (polystyrene), a plasticizer (tricresyl phosphate), and xylene. It facilitates the protection of stains and can dry quickly.

Application

D.P.X. has been used as a mounting medium for mounting:
  • rat brain sections for immunohistochemistry studies
  • mouse small intestine sections for morphometry studies
  • gastrointestinal tract sections of rats for immunohistochemistry

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Target Organs

Central nervous system,Liver,Kidney, Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

77.0 °F - closed cup

Flash Point(C)

25 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Terry L Powley et al.
Autonomic neuroscience : basic & clinical, 183, 36-48 (2014-03-25)
The pylorus is innervated by vagal mechanoreceptors that project to gastrointestinal smooth muscle, but the distributions and specializations of vagal endings in the sphincter have not been fully characterized. To evaluate their organization, the neural tracer dextran biotin was injected
Guo-Qing Chen et al.
Cell death & disease, 8(5), e2789-e2789 (2017-05-12)
Autophagy has a key role in metabolism and impacts on tumorigenesis. Our previous study found that halofuginone (HF) exerts anticancer activity in colorectal cancer (CRC) by downregulating Akt/mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway. But whether and how
Yue-Yang Liu et al.
CNS neuroscience & therapeutics, 23(7), 567-579 (2017-05-10)
Pseudoginsenoside-F11 (PF11), an ocotillol-type ginsenoside, has been reported to exert wide-ranging neuroprotective properties. The aim of this study was to investigate the effect and potential mechanisms of PF11 on the autophagic/lysosomal pathway following ischemic stroke. Male Sprague-Dawley rats underwent permanent
Matteo Riva et al.
Biology open, 8(9) (2019-09-13)
Recently, several promising treatments for high-grade gliomas (HGGs) failed to provide significant benefit when translated from the preclinical setting to patients. Improving the animal models is fundamental to overcoming this translational gap. To address this need, we developed and comprehensively
Jill-Desiree Brederson et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society (2018-02-13)
Osteoarthritis (OA) is a degenerative form of arthritis that can result in loss of joint function and chronic pain. The pathological pain state that develops with OA disease involves plastic changes in the peripheral and central nervous systems, however, the
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