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Key Documents

266A-1

Sigma-Aldrich

Human Placental Lactogen (hPL) Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (266A-14)
vial of 0.5 mL concentrate (266A-15)
bottle of 1.0 mL predilute (266A-17)
vial of 1.0 mL concentrate (266A-16)
bottle of 7.0 mL predilute (266A-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

control

placenta

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

General description

Human placental lactogen (hPL), also previously known as "human chorionic somatomammotropin", is a 22 kD protein with partial homology to growth hormone. hPL is first detectable in the maternal serum in the fifth week of gestation and reaches a plateau by the thirty-fourth week. hPL has been demonstrated by immunochemistry in the syncytiotrophoblastic cells of choriocarcinoma. A rare variant of trophoblastic tumor has been reported in the testis with resemblance to uterine placental site trophoblastic tumor. It consists purely of intermediate trophoblasts which are diffusely positive for hPL and focally for ß-hCG.

Quality


IVD
IVD
IVD
RUO

Linkage

Human Placental Lactogen (hPL) Positive Control Slides, Product No. 266S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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I Ming Shih et al.
The American journal of surgical pathology, 28(9), 1177-1183 (2004-08-19)
Human trophoblast is composed of a heterogeneous population of cells, which give rise to a variety of trophoblastic tumors and tumor-like lesions. In this report, we analyzed the expression pattern of the p63 gene, a transcription factor belonging to the
T M Ulbright et al.
The American journal of surgical pathology, 21(3), 282-288 (1997-03-01)
We report two unusual forms of testicular trophoblastic tumor. One was a mixed germ cell tumor in a 19-year-old man that had a predominant component of nodules of cytotrophoblast cells with only rare syncytiotrophoblast cells. These nodules of "monophasic" choriocarcinoma

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