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Key Documents

05420

Sigma-Aldrich

Albumin from human serum

lyophilized powder, ≥95.0% (agarose gel electrophoresis)

Synonym(s):

HSA

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
eCl@ss:
42010201

biological source

human

Quality Level

Assay

≥95.0% (agarose gel electrophoresis)

form

lyophilized powder

mol wt

monomer calculated mol wt 66478 Da

technique(s)

tissue culture: suitable

impurities

HIV I and HIVII, HCV and HBsAg, tested negative

pH

7.0±0.2

solubility

H2O: 50 mg/mL, clear to slightly hazy, yellow

UniProt accession no.

storage temp.

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

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Biochem/physiol Actions

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

Other Notes

View more information on human serum albumin.
Review: Serum albumin

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Penelope Rice et al.
Journal of immunology (Baltimore, Md. : 1950), 174(6), 3676-3685 (2005-03-08)
We previously demonstrated that exposure to febrile-range hyperthermia (FRH) accelerates pathogen clearance and increases survival in murine experimental Klebsiella pneumoniae peritonitis. However, FRH accelerates lethal lung injury in a mouse model of pulmonary oxygen toxicity, suggesting that the lung may
T. Peters, Jr.
Adv. Prot. Chem., 37, 161-161 (1985)
Indu Sharma et al.
Fertility and sterility, 94(5), 1639-1646 (2009-12-01)
To investigate the in vitro effects of atorvastatin on lipopolysaccharide (LPS)-induced gene expression in endometrial-endometriotic stromal cells. In vitro experimental study using flow cytometry, ELISA, semiquantitative reverse transcriptase polymerase chain reaction, and Western blot. Postgraduate Institute of Medical Education and
Zhenping Liu et al.
The review of diabetic studies : RDS, 5(4), 232-244 (2009-03-19)
The influence of glucose and fatty acids on beta-cell function is well established whereas little is known about the role of amino acids (AAs). Islets isolated from NMRI mice were incubated overnight. After preincubation, isolated islets as well as clonal
Kotaro Suzuki et al.
Cell, 134(3), 485-495 (2008-08-12)
Mast cells are known to play a pivotal role in allergic diseases. Cross-linking of the high-affinity receptor for IgE (FcepsilonRI) leads to degranulation and allergic inflammation; however, the regulatory mechanisms of IgE-dependent exocytosis remain unknown. We show here that IkappaB

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