Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

D5879

Sigma-Aldrich

Dimethyl sulfoxide

ReagentPlus®, ≥99.5%

Synonym(s):

DMSO

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
MDL number:
UNSPSC Code:
12191502
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.7 (vs air)

Quality Level

vapor pressure

0.42 mmHg ( 20 °C)

product line

ReagentPlus®

Assay

≥99.5%

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

immunoblotting: suitable

impurities

≤0.1% water (Karl Fischer)

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: soluble(lit.)
acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Dimethyl sulfoxide is an amphipathic molecule, soluble in both aqueous and organic solvents. It is commonly used as an aprotic solvent and also as a reagent in organic synthesis.

Application

DMSO has been used as a medium to prepare a chemiluminescence reagent that can be a substitute to commercially-available enhanced chemiluminescence kits for use in immunoblotting technique.

Biochem/physiol Actions

DMSO is a highly polar substance that can be used as an industrial solvent for organic and inorganic chemicals. It is also used as a protectant during cold storage of living cells. It is also useful for the oxidation of thiols and disulfides to sulfonic acids.

Packaging

Note: D5879-1L in glass bottle /D5879-1L-D in poly bottle.

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Julia L Zehr et al.
Biology of reproduction, 72(5), 1087-1094 (2004-12-31)
This study investigated whether prenatal androgen exposure, social rank, and body weight are factors regulating pubertal development in outdoor-housed female rhesus monkeys. Subjects' mothers received injections of testosterone enanthate (20 mg/ wk), flutamide (an androgen receptor blocker, 30 mg/kg twice
M Bouquet et al.
Molecular reproduction and development, 40(1), 110-115 (1995-01-01)
In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to
M Ruhnke et al.
Journal of clinical microbiology, 32(9), 2092-2098 (1994-09-01)
After repeated use of fluconazole for therapy of oropharyngeal candidosis, the emergence of in vitro fluconazole-resistant Candida albicans isolates (MIC, > or = 25 micrograms/ml) together with oral candidosis unresponsive to oral dosages of up to 400 mg of fluconazole
Sun-A Ock et al.
Cell transplantation, 20(8), 1231-1239 (2011-02-08)
Dimethyl sulfoxide (DMSO), a commonly used cryoprotectant in cryopreservation procedures, is detrimental to viability of cells. In this view point, a comparative study was carried out to evaluate the effect of DMSO on porcine mesenchymal stem cells (pMSCs). We compared
Levent Keskintepe et al.
Journal of assisted reproduction and genetics, 26(11-12), 629-635 (2009-12-08)
Cryopreservation of blastocysts, especially those subjected to the trauma due to blastomere biopsy for the purposes of pre-implantation genetic screening (PGS), requires significant optimization. Laboratory and clinical outcomes were compared to determine the effect of two different cryopreservation techniques on

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service