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SMB01352

Sigma-Aldrich

Prolylphenylalanine

≥95% (HPLC)

Synonym(s):

Pro-Phe, N-L-Prolyl-L-phenylalanine, N-Prolylphenylalanine, L-Prolyl-L-phenylalanine, Proline phenylalanine dipeptide, Proline-phenylalanine dipeptide, Prolyl-phenylalanine

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About This Item

Empirical Formula (Hill Notation):
C14H18N2O3
CAS Number:
Molecular Weight:
262.30
MDL number:
UNSPSC Code:
12352209

Quality Level

Assay

≥95% (HPLC)

form

solid

color

white to beige

mp

250—251 °C

storage temp.

2-8°C

SMILES string

OC(=O)C(Cc1ccccc1)NC(=O)C2CCCN2

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General description

Prolylphenylalanine, a dipeptide composed of proline and phenylalanine, exhibits considerable potential for diverse applications in both biochemical and biomedical research. It is an incomplete breakdown product of protein digestion or protein catabolism, found in urine. In biochemical studies, it serves as a substrate for various enzymes, including dipeptidyl peptidase-4 (DPP-4) and prolylcarboxypeptidase (PCP), shedding light on essential biochemical pathways related to protein digestion and metabolism. Moreover, prolylphenylalanine functions as a versatile tool for exploring protein interactions with other molecules, probing enzyme active sites, and identifying potential drug targets. Furthermore, it can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983). Within biomedical research, prolylphenylalanine is the focus of extensive exploration as a potential therapeutic agent for a range of conditions, including hypertension, cardiovascular disease, and Alzheimer′s disease.

Application

Prolylphenylalanine can be used in biochemical and metabolomics research applications

Features and Benefits

  • Suitable for Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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