PHR1518

Polydimethylsiloxane

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Dimethylpolysiloxane, Polydimethylsiloxane
• CAS Number: 9016-00-6
• MDL number: MFCD00084411
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to Ph. Eur. S0600000; traceable to USP 1546300
• API family: polydimethylsiloxane
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• InChI: 1S/C2H6OSi/c1-4(2)3/h1-2H3
• InChI key: SEUDSDUUJXTXSV-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Poly(dimethylsiloxane) [PDMS] is a polymer. It is a stable silicone rubber. It has been used as ion selective membrane for ion-sensitive field-effect transistors, as spring material in accelerometers, elastomer on a tactile sensor and as flexible encapsulation material in decouple sensors.

Application

It was used in a study performed to understand its molecular weight and molecular weight distribution by off-line coupling of GPC with MALDI mass spectrometer.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Clear, colorless fluid polymer useful as a stationary phase in gas chromatography and as an anti-foaming agent.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7823 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): 609.8 °F - closed cup
• Flash Point(C): 321 °C - closed cup