92986

N-Propionylglycine

analytical standard

• Synonym(s): 2-(Propionylamino)acetic acid, N-(1-Oxopropyl)glycine, NSC 158539, Propionyl glycine
• Empirical Formula (Hill Notation): C₅H₉NO₃
• CAS Number: 21709-90-0
• Molecular Weight: 131.13
• Beilstein: 1759032
• MDL number: MFCD09049674
• UNSPSC Code: 12352209
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(CNC(CC)=O)=O
• InChI: 1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)
• InChI key: WOMAZEJKVZLLFE-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase.

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3