80818

(2S)-2-(5-Bromo-6-methoxynaphthalen-2-yl)propanoic acid

pharmaceutical impurity standard

• Synonym(s): Naproxen Impurity C (PhEur), (αS)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid, (2S)-2-(5-Bromo-6-methoxy-2-naphthyl)propionic acid, (S)-5-Bromonaproxen
• Empirical Formula (Hill Notation): C₁₄H₁₃BrO₃
• CAS Number: 84236-26-0
• Molecular Weight: 309.16
• Beilstein: 5278975
• EC Number: 282-475-6
• MDL number: MFCD22381000
• UNSPSC Code: 12352200
• PubChem Substance ID: 329769057
• NACRES: NA.24

Properties

• Quality Level: 100
• API family: naproxen
• Assay: ≥98.0% (HPLC)
• optical activity: [α]/D 46±4°, c = 1 in chloroform
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤0.5% water
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[C@H](C(O)=O)C1=CC2=CC=C(OC)C(Br)=C2C=C1
• InChI: 1S/C14H13BrO3/c1-8(14(16)17)9-3-5-11-10(7-9)4-6-12(18-2)13(11)15/h3-8H,1-2H3,(H,16,17)/t8-/m0/s1
• InChI key: JZRWXNBIQCMXSU-QMMMGPOBSA-N

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335,H361fd,H411
• Precautionary Statements: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable