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Metol

ACS reagent, for spectrophotometric det. of inorganic phosphate, ≥99.0%

Synonym(s):

4-(Methylamino)phenol hemisulfate salt, Metol

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About This Item

Linear Formula:
C7H9NO · 1/2H2SO4
CAS Number:
Molecular Weight:
172.19
Beilstein:
3919382
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

Assay

≥99.0% (NT)
≥99.0%

form

crystals

autoignition temp.

989 °F

quality

for spectrophotometric det. of inorganic phosphate

technique(s)

UV/Vis spectroscopy: suitable

ign. residue

≤0.1%

mp

260 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear

application(s)

general analytical

SMILES string

OS(O)(=O)=O.CNc1ccc(O)cc1.CNc2ccc(O)cc2

InChI

1S/2C7H9NO.H2O4S/c2*1-8-6-2-4-7(9)5-3-6;1-5(2,3)4/h2*2-5,8-9H,1H3;(H2,1,2,3,4)

InChI key

ZVNPWFOVUDMGRP-UHFFFAOYSA-N

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General description

Metol (4-methylaminophenol sulphate) is white crystalline which helps in determination of phosphate by reduction reaction of phosphomolybdic acid to molybdenum blue with intense colour. It is used as reducing agent. A solution of Metol could be prepared by dissolving a known amount in water with hydrated sodium sulphite along with which few drops of Brij needs to be added.

Legal Information

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

494.6 °F - closed cup

Flash Point(C)

257 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Improved method for the automatic determination of serum inorganic phosphate.
D S Young
Journal of clinical pathology, 19(4), 397-399 (1966-07-01)
A single-solution method for the determination of soluble phosphate in sea water.
Murphy, James, and J. P. Riley.
J. Mar. Biol. Ass. U.K., 37, 9-14 (1958)
Ayman A Gouda et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 130, 480-487 (2014-05-13)
Simple, rapid and accurate high performance liquid chromatographic (HPLC) and spectrophotometric methods are described for determination of antihistaminic acrivastine in capsules. The first method (method A) is based on accurate, sensitive and stability indicating chromatographic separation method. Chromolith® Performance RP-18e

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