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44112

Sigma-Aldrich

Polysorbate 20

tested according to Ph. Eur.

Synonym(s):

Polysorbatum 20

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About This Item

CAS Number:
9005-64-5
MDL number:
MFCD00165986
UNSPSC Code:
12352201
NACRES:
NA.21

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

200

description

non-ionic

form

liquid

mol wt

~1228 g/mol

CMC

0.06

transition temp

cloud point 76 °C

HLB

16.7

application(s)

pharmaceutical (small molecule)

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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Application


  • Evaluating a Modified High Purity Polysorbate 20 Designed to Reduce the Risk of Free Fatty Acid Particle Formation.: The research evaluates a modified high purity form of Polysorbate 20, designed to mitigate the formation of free fatty acid particles. This modification potentially enhances the stability and safety of biopharmaceutical formulations (Doshi et al., 2021).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

527.0 °F - Pensky-Martens closed cup

Flash Point(C)

275 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK1571
BCCJ0928
BCCG7364
BCCG9420
BCCG5486

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Gunasekaran Dhandapani et al.
mAbs, 11(3), 583-592 (2019-01-09)
We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use of detergent aggregates capable of efficiently capturing Ab while rejecting hydrophilic

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