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33988

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Clopidol

VETRANAL®, analytical standard

Synonym(s):

3,5-Dichloro-2,6-dimethyl-4-pyridinol

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About This Item

Empirical Formula (Hill Notation):
C7H7Cl2NO
CAS Number:
Molecular Weight:
192.04
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cc1nc(C)c(Cl)c(O)c1Cl

InChI

1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)

InChI key

ZDPIZLCVJAAHHR-UHFFFAOYSA-N

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General description

Clopidol belongs to the anticoccidial class of drugs.

Application

Clopidol may be used as a reference standard for the determination of clopidol in:
  • Bovine muscle, animal tissues and eggs by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS).
  • Environmental water samples by on-line solid phase extraction (SPE) and ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS).
  • Chicken processed foods and muscles by solid-supported liquid extraction (SLE) clean-up and LC-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Multi-residue methodology for the determination of 16 coccidiostats in animal tissues and eggs by hydrophilic interaction liquid chromatography-Tandem mass spectrometry
Dasenaki ME and Thomaidis NS
Food Chemistry, 275(5-6), 668-680 (2019)
E M Mattern et al.
Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 190(1), 25-30 (1990-01-01)
A fully automated HPLC determination of the coccidiostat meticlorpindol in whole egg, egg white and yolk is described. The sample homogenate is dialysed on-line against water. The dialysate is concentrated on-line on a short reversed-phase (RP) column. The contents of
L G Ekström et al.
Journal - Association of Official Analytical Chemists, 67(5), 955-957 (1984-09-01)
A method has been developed for the determination of clopidol residues in chicken tissues. After extraction and cleanup, clopidol is esterified in a 2-phase system to clopidol propionate, which is determined by gas chromatography. The 2-phase system includes, in addition
Simultaneous determination of multi-class veterinary drugs in chicken processed foods and muscle using solid-supported liquid extraction clean-up.
Yoshikawa S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1057(5-6), 15-23 (2017)
A Arakawa et al.
Veterinary parasitology, 38(1), 55-60 (1991-01-01)
Feed additive anticoccidials currently used in Japan were examined for possible effects on oocyst sporulation of Eimeria tenella. Monensin, salinomycin, lasalocid, amprolium plus ethpabate, amporolium plus ethopabate plus sulfaquinoxaline, clopidol, or nicarbazin were given to chickens continuously via the feed

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