33510

1,10-Phenanthroline monohydrate

ACS reagent, puriss. p.a., ≥99.5% (calc. to the dried substance), for redox titration

• Synonym(s): o-Phenanthroline monohydrate
• Empirical Formula (Hill Notation): C₁₂H₈N₂ · H₂O
• CAS Number: 5144-89-8
• Molecular Weight: 198.22
• Beilstein: 4008096
• EC Number: 200-629-2
• MDL number: MFCD00149973
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648856
• NACRES: NA.21

Properties

• grade: ACS reagent; puriss. p.a.
• Quality Level: 200
• Assay: ≥99.5% (calc. to the dried substance); 8.5-9.5% water basis
• technique(s): titration: suitable
• impurities: 8.5-9.5% water
• ign. residue: ≤0.05% (as SO₄)
• mp: 100-104 °C (lit.); 97-102 °C
• suitability: passes test for iron detection; passes test for redox indicator
• SMILES string: O.c1cnc2c(c1)ccc3cccnc23
• InChI: 1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2
• InChI key: PPQJCISYYXZCAE-UHFFFAOYSA-N

Description

General description

1,10-Phenanthroline monohydrate is the hydrated form of o-phenanthroline.

Application

1,10-Phenanthroline monohydrate (phen) may be used in the photochemical quantification of Fe³⁺ and total iron in mineral samples. It may be used as starting reagent for the preparation of 5-nitro-1,10-phenanthroline.

When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H301 - H410
• Precautionary Statements: P264 - P273 - P301 + P310 - P391 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves