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Supelco

Fusarenon X

analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one

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About This Item

Empirical Formula (Hill Notation):
C17H22O8
CAS Number:
Molecular Weight:
354.35
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CC(=O)O[C@@H]1[C@@H](O)[C@H]2O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@]1(C)[C@]24CO4

InChI

1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9?,11-,12-,13-,14?,15?,16?,17?/m1/s1

InChI key

XGCUCFKWVIWWNW-LTNYHXKASA-N

General description

Fusarenon X is a trichothecene mycotoxin isolated from Fusarium nivale.

Application

Fusarenon X may be used as a reference standard for the determination of fusarenon X in barley, wheat and corn samples by high-performance thin-layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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High-performance thin-layer chromatographic determination of deoxynivalenol, fusarenon-X, and nivalenol in barley, corn, and wheat.
Trucksess M W, et al.
Journal of Agricultural and Food Chemistry, 35(4), 445-448 (1987)
General pharmacological studies of fusarenon-X, a trichothecene mycotoxin from Fusarium species.
Matsuoka Y, et al.
Toxicology and Applied Pharmacology, 50(1), 87-94 (1979)
J Li et al.
The Journal of veterinary medical science, 59(3), 191-199 (1997-03-01)
Male 5-week-old Wistar rats orally (po) administered with fusarenon-X (FX) 1.5 mg/kg and control rats po-treated with distilled water were sacrificed at 0-48 hr after gavage. FX-administered rats showed significant dilatation of the stomach with increased fluid contents at 1-24
S Bony et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(3), 457-465 (2006-12-13)
This study aims to assess the genotoxic potential of nivalenol (NIV) and fusarenon X (FusX), produced by various Fusarium on cereals. Toxins were applied in time and dose-dependent experiments to the human enterocyte-like Caco-2 cell-line, both in dividing (undifferentiated) and
K Miura et al.
Toxicology, 127(1-3), 195-206 (1998-08-12)
The effects of fusarenon-X (12,13-epoxytrichothecene; FX) on mouse thymus and T-cell subpopulations were studied. In mice that received three intraperitoneal injections of FX, the thymus showed severe atrophy, the thymic cortex almost completely disappeared, and the total number of thymocytes

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