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32593

Supelco

Cambendazole

VETRANAL®, analytical standard

Synonym(s):

Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate

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About This Item

Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
26097-80-3
Molecular Weight:
302.35
Beilstein:
563292
EC Number:
247-459-5
MDL number:
MFCD00864552
UNSPSC Code:
41116107
PubChem Substance ID:
329754047
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)OC(=O)Nc1ccc2[nH]c(nc2c1)-c3cscn3

InChI

1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)

InChI key

QZWHWHNCPFEXLL-UHFFFAOYSA-N

General description

Cambendazole is classified under the family of benzimidazole anthelmintic compounds.

Application

Cambendazole may be used as an analytical reference standard for the determination of the analyte in:
  • Bovine muscle samples by ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS/MS) operating in ESI mode.
  • Bovine milk samples by LC-ESI-MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Product No.
Description
Pricing

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK1453
BCCF0930
BCBZ9917
BCBW6201
BCBS4988V

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R N Beech et al.
Genetics, 138(1), 103-110 (1994-09-01)
Benzimidazole anthelmintics are the most common chemotherapeutic agents used to remove intestinal helminths from farm animals. The development of drug resistance within helminth populations is wide-spread and can render these drugs essentially useless. The mechanism of benzimidazole resistance appears to
G C Coles et al.
Research in veterinary science, 45(1), 50-53 (1988-07-01)
The growth, using freshly cultured Escherichia coli with ampicillin or heat-treated lyophilised E coli as a food source, of the larvae of the mouse nematode Nematospiroides dubius and the infectivity of resulting third stage larvae were determined. Concentrations of E
Strongyloides ratti and S. stercoralis: effects of cambendazole, thiabendazole and mebendazole in vitro.
D I Grove et al.
Revista do Instituto de Medicina Tropical de Sao Paulo, 28(2), 97-103 (1986-03-01)
R F Bento et al.
Revista do Instituto de Medicina Tropical de Sao Paulo, 35(4), 373-375 (1993-07-01)
A 15 year old male patient was diagnosed as being infected with the nematode Lagochilascaris minor, presenting as abscesses over the left mastoid region, and invading the temporal bone, mastoid sinuses and possibly the CNS. Surgical drainage and administration of
New method for the analysis of flukicide and other anthelmintic residues in bovine milk and liver using liquid chromatography-tandem mass spectrometry.
Kinsella B, et al.
Analytica Chimica Acta, 637(1-2), 196-207 (2009)
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